Four limonoids from the seeds extract of Sandoricum koetjape.

摘要: Three andirobin- and one trijugin-class limonoids, named koetjapins A-D (1–4), have been isolated from the seed extracts of Sandoricum koetjape. The structures these compounds were determined by extensive NMR mass spectral data, chemotaxonomic significance limonoids in family Meliaceae is highlighted. Preliminary biological activity showed that only compound 4 has significant inhibitory against P-388 cells, while antibacterial tests none active.