Prognostic Value of Masked Uncontrolled Hypertension Defined by Different Ambulatory Blood Pressure Criteria.

摘要: Background Masked uncontrolled hypertension (MUCH), that is, nonhypertensive clinic but high out-of-office blood pressure (BP) in treated patients is at increased cardiovascular risk than controlled (CH), and BP. Using ambulatory BP, MUCH can be defined as daytime and/or nighttime 24-hour BP above thresholds. It unclear whether different definitions of have similar prognostic information. This study assessed the value by criteria. Methods Cardiovascular events were evaluated 738 hypertensive with Among them, participants classified having CH or (BP ≥135/85 mm Hg) regardless (group 1), ≥120/70 2), ≥130/80 3), only 4), 5), + 6). Results We detected 215 (29%), 357 (48.5%), 275 (37%), 42 (5.5%),184 (25%) 173 (23.5%) from group 1 to 6, respectively. During follow-up (10 ± 5 years), 148 occurred MUCH. After adjustment for covariates, compared CH, adjusted hazard ratio (95% confidence interval) was 2.01 (1.45-2.79), 1.53 (1.09-2.15), 1.69 (1.22-2.34), 1.52 (0.80-2.91), 1.15 (0.74-1.80), 2.29 (1.53-3.42) Conclusions The impact according various may different.