The Solubility and Conformation of Protected Tri- to Heptapeptides in a Variety of Organic Solvents and the Classification of Organic Solvents Based on Their Solvating Potential for Protected Peptides
作者： Mitsuaki Narita , Jin-Shik Lee , Shizue Hayashi , Yasunobu Yamazaki , Mitsuo Hitomi
DOI: 10.1246/BCSJ.66.494
关键词: Chemistry 、 Acceptor 、 Solvation 、 Solubility 、 Hydrogen bond 、 Donor number 、 Organic chemistry 、 van der Waals force 、 Intermolecular force 、 Solvent effects
摘要: The solubility in a variety of organic solvents was examined for 75 kinds protected tri- to heptapeptide fragments E. coli ribosomal protein L7/L12. were classified into six groups mainly by considering their solvating potential and supplementarily using acceptor number (AN) donor (DN). result the classification practically explained DN AN solvents, indicating that electron-donating or -accepting ability is much more important solvation peptides than form van der Waals interactions. Nevertheless, mechanism could be two types intermolecular interactions, namely, hydrogen bonding values peptieds, difined previous paper, properly reflected β-sheet-structure stability of...
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