作者: Maurizio Muraca , Rocco Orlando , Mario Strazzabosco , Gino Nassuato , Flavio Lirussi
DOI: 10.1007/978-3-642-72631-6_22
关键词: Unconjugated bilirubin 、 Clinical value 、 Serum bilirubin 、 Clinical significance 、 Pharmacology 、 Bilirubin 、 Hepatobiliary disease 、 Chemistry 、 Dimethyl ester 、 Conjugated bilirubin
摘要: The potential clinical value of serum bilirubin cannot be fully exploited because analytical problems affecting in particular the determination conjugated pigment fraction. In this review, some recent methodological advances are described which now allow direct quantitation unconjugated bilirubin, monoconjugate, and diconjugate human serum. This novel methodology has greatly improved our understanding mechanisms determining levels serum, changes occurring pathological conditions.