Bone Nanostructure and its Relevance for Mechanical Performance, Disease and Treatment
作者： Peter Fratzl , Himadri S. Gupta , Paul Roschger , Klaus Klaushofer
DOI: 10.1002/9783527628155.NANOTECH060
关键词: Osteogenesis imperfecta 、 Biomedical engineering 、 Bone material 、 Osteoporosis 、 Density distribution 、 Materials science 、 Nanocomposite 、 Mineral particles 、 Nanostructure 、 Bone mineral 、 Mineralogy
摘要: The remarkable mechanical properties of bone are due to its hierarchical structure which is optimized at all levels hierarchy. At the lowest level, a nanocomposite collagen and mineral particles. quality this material crucial for performance as whole. In chapter we review composition nanoscale, report several examples on how may be affected by disease or treatment strategies. Keywords: bone; hydroxyapatite; collagen; osteoporosis; osteogenesis imperfecta; fluorosis; bone density distribution; small-angle X-ray scattering
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