作者: Barbara Sennino , David Bellovin , Thomas Brennan , David Busha
DOI:
关键词: Chemistry 、 Cancer research 、 Domain (software engineering) 、 CD80 、 Cancer 、 Extracellular 、 Immune system 、 Cancer treatment 、 Molecular biology
摘要: This application relates to CD80 (B7-1) extracellular domain (ECD) polypeptides and CD80-ECD fusion molecules their use in treatment of cancer, both alone combination with other therapeutic agents, such as immune stimulating agents PD-1/PD-L1 inhibitors.