A novel plausible mechanism of NSAIDs-induced apoptosis in cancer cells: the implication of proline oxidase and peroxisome proliferator-activated receptor

作者: Adam Kazberuk , Ilona Zareba , Jerzy Palka , Arkadiusz Surazynski

DOI: 10.1007/S43440-020-00140-Z

关键词: Peroxisome proliferator-activated receptorBiochemistryReactive oxygen speciesProline oxidaseChemistryApoptosisProline dehydrogenaseCancer cellPeroxisomeAutophagy

摘要: … Another evidence for COX-independent effect of NSAIDs was provided by studies on chiral … Targeting PPARγ was used for the type 2 diabetes treatment with thiazolidinedione (TZD) …

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