作者: Sinuon Muth , Somphou Sayasone , Sophie Odermatt-Biays , Samlane Phompida , Socheat Duong
DOI: 10.1016/S0065-308X(10)72007-8
关键词: Veterinary medicine 、 Population 、 Mass drug administration 、 Prevalence 、 Geography 、 Public health 、 Helminthiasis 、 Schistosomiasis 、 Schistosoma 、 Schistosoma mekongi 、 Socioeconomics
摘要: Schistosomiasis found in communities along the Mekong River Cambodia and Lao People's Democratic Republic (Lao PDR) is caused by blood fluke Schistosoma mekongi. Early observations on patients 1957 revealed severe intestinal hepatosplenic disease. High mortality rates widespread disease were reported from provinces of northern (Stung Treng Kratie) southern PDR (Champasack) early 1970s 1990s. Control programmes built around mass drug administration, with praziquantel, combined information education campaigns, carried out. In Cambodia, such started 1995 endemic sustained until today; these efforts resolved public health problem schistosomiasis mekongi led to a significant reduction transmission. PDR, interventions late 1980s, but suffered several interruptions which permitted transmission resume. Today, number small foci continue show substantial prevalence rates. The snail intermediate host, Neotricula aperta, present some its tributaries. There evidence that might not yet have reached full geographical distribution emphasising need sustain vigilance. New infections S. occur population travellers alike. Comprehensive guidelines for elimination bilateral between are required.