In vivo biocompatibility studies of poly( n-vinyl 2-pyrrolidone/itaconic acid) hydrogels synthesized by γ-rays
作者： S Özdemir , E Özdemir , R Tunca , R Hazıroǧlu , M Şen
DOI: 10.1016/S0168-583X(03)01109-1
关键词: Total immunoglobulin 、 Polymer chemistry 、 Itaconic acid 、 Self-healing hydrogels 、 In vivo 、 In vivo biocompatibility 、 Nuclear chemistry 、 Chemistry 、 Biocompatibility 、 Histology 、 2-Pyrrolidone
摘要: Abstract In this study, poly(n-vinyl 2-pyrrolidone/itaconic acid) hydrogels have been synthesized by γ-rays in different compositions and their biocompatibility investigated as vivo some biochemical parameters of mice serum histology tissues examined. By these purposes, (P(VP/IA)) were implanted to hypersensitive (BALB/c). One a half months after implantation, hydrogel animals sacrificed ether anesthesia the area contacted with tissue was light microscope for histopathological identification tissue. Then total immunoglobulin E (IgE) level determined ELISA. Differential white cell count also made better understanding reaction between These can be directly used biomedical materials.
harvard.edu
elsevier.com
sci-hub.se 参考文章(9)
William Francis Ganong, Review of Medical Physiology ,(1969)
Norman F. Cheville, Introduction to Veterinary Pathology ,(1988)
Murat Şen, Ömer Kantoğlu, Olgun Güven, The effect of external stimuli on the equilibrium swelling properties of poly(N-vinyl 2-pyrrolidone/itaconic acid) poly-electrolyte hydrogels Polymer. ,vol. 40, pp. 913- 917 ,(1999) , 10.1016/S0032-3861(98)00320-6
Francine Anfosso, Christian Demeure, Michel Delaage, Rose Cheballah, Françoise Bello, Alain Bourgois, Conformational differences of human IgE on hydrophobic and hydrophilic solid phases detected by monoclonal antibodies Molecular Immunology. ,vol. 24, pp. 1129- 1134 ,(1987) , 10.1016/0161-5890(87)90158-1
P. Pradelles, J. Grassi, J. Maclouf, Enzyme immunoassays of eicosanoids using acetylcholine esterase as label: an alternative to radioimmunoassay. Analytical Chemistry. ,vol. 57, pp. 1170- 1173 ,(1985) , 10.1021/AC00284A003
D.F. Williams, A model for biocompatibility and its evaluation. Journal of Biomedical Engineering. ,vol. 11, pp. 185- 191 ,(1989) , 10.1016/0141-5425(89)90138-6
LYNN NYE, T. G. MERRETT, J. LANDON, R. J. WHITE, A detailed investigation of circulating IgE levels in a normal population Clinical & Experimental Allergy. ,vol. 5, pp. 13- 24 ,(1975) , 10.1111/J.1365-2222.1975.TB01832.X
James M. Seeger, Michael D. Ingegno, Emmanuel Bigatan, Nina Klingman, Drew Amery, Chris Widenhouse, Eugene P. Goldberg, Hydrophilic surface modification of metallic endoluminal stents Journal of Vascular Surgery. ,vol. 22, pp. 327- 336 ,(1995) , 10.1016/S0741-5214(95)70148-6
Robert David Bagnall, An approach to the soft tissue/synthetic material interface Journal of Biomedical Materials Research. ,vol. 11, pp. 939- 946 ,(1977) , 10.1002/JBM.820110612