Decompressive Craniectomy in Diffuse Traumatic Brain Injury
作者： D. James Cooper , Jeffrey V. Rosenfeld , Lynnette Murray , Yaseen M. Arabi , Andrew R. Davies
关键词: Confidence interval 、 Glasgow Outcome Scale 、 Refractory 、 Intracranial pressure 、 Clinical trial 、 Odds ratio 、 Decompressive craniectomy 、 Intensive care unit 、 Anesthesia 、 Medicine 、 Surgery
摘要: Patients in the craniectomy group, as compared with those standard-care had less time intracranial pressures above treatment threshold (P<0.001), fewer interventions for increased pressure (P<0.02 all comparisons), and days intensive care unit (ICU) (P<0.001). However, patients undergoing worse scores on Extended Glasgow Outcome Scale than receiving standard (odds ratio a score 1.84; 95% confidence interval [CI], 1.05 to 3.24; P = 0.03) greater risk of an unfavorable outcome ratio, 2.21; CI, 1.14 4.26; 0.02). Rates death at 6 months were similar group (19%) (18%). Conclusions In adults severe diffuse traumatic brain injury refractory hypertension, early bifrontotemporoparietal decompressive decreased length stay ICU but was associated more outcomes. (Funded by National Health Medical Research Council Australia others; DECRA Australian Clinical Trials Registry number, ACTRN012605000009617.)
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