Prostaglandin E1 reduces myocardial reperfusion injury by inhibiting proinflammatory cytokines production during cardiac surgery.

作者: Takae Kawamura , Noriko Nara , Mamoru Kadosaki , Katsuya Inada , Shigeatu Endo

DOI: 10.1097/00003246-200007000-00004

关键词: CytokineIschemiaTumor necrosis factor alphaProinflammatory cytokineCardiac surgeryInterleukinProstaglandin E1AnesthesiaMedicineCardiopulmonary bypass

摘要: ObjectiveTo determine the influence of prostaglandin E1 (PGE1) on cytokine balance and myocardial protection during cardiac surgery.DesignProspective, randomized, nonblinded study.SettingUniversity hospital.PatientsA total 19 patients cardiopulmonary bypass undergoing surgery.Inter

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