The participation of soluble factors in the ω-oxidation of fatty acids in the liver of the sheep
作者： W. Robert Hare , Klaus W. J. Wahle
DOI: 10.1007/BF02544002
关键词: Superoxide dismutase 、 Fatty acid 、 Biochemistry 、 Chemistry 、 Metabolism 、 Hydroxylation 、 Enzyme 、 Fatty acid-binding protein 、 Biological pathway 、 Catalase
摘要: The removal of soluble components from an ovine hepatic microsomal preparation decreased the ω-hydroxylation dodecanoic and hexadecanoic acids. results suggest that one or more play a role in fatty possible roles reaction catalase (known to stimulate desaturations acids alkylglycerols) superoxide dismutase were investigated. addition these enzymes complete (but not washed) stimulated both initial subsequent dehydrogenation reactions ω-oxidation pathway. similarity effects stimulation two different steps pathway agents are acting indirectly by removing active oxygen species rather than directly on acid ω-hydroxylation.
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