Comparable Safety of Blood Collection in “High-risk” Autologous Donors Versus Non-High-risk Autologous and Directed Donors in a Hospital Setting

摘要: The safety of autologous blood donation by "high-risk" patients (those with some preexisting medical conditions) has been questioned. authors reviewed 1393 consecutive records (207 high-risk [HRA], 665 non-high-risk [NHRA], and 521 directed donors [DD]) to determine the outcome HRA as compared other at their center. group included a history significant coronary artery on cerebral vascular disease, recent seizures, cardiac arrhythmia, chronic heart failure, valvular or congenital symptomatic dyspnea, insulin-dependent diabetes and/or current therapy two more antihypertensive medications. Those designated NHRA were all donors; DD met criteria for homologous donation. Donor characteristics including predonation hematocrit, pre- postdonation mean arterial pressure rates similar in groups. Eight (3.9%) had reactions, 21 (3.2%) 23 (4.4%), difference that was without statistical significance. reaction rate (HRA NHRA) 3.4%. No differences symptoms reported, hemodynamics severity observed among three groups (P > .05). A multiple logistic regression performed within risk factor categories listed above medication classes beta blockers, glycosides, calcium-channel agents, nitrates, antiarrhythmic agents (chi 2 = 14.9; P .0006). Only first-time .0001) glycoside usage .04) positively associated an untoward reaction. conclude is least safe who meet population setting.