Neurobehavioral and autonomic alterations in adults with obstructive sleep apnea.

摘要: Abstract Objective Obstructive sleep apnea (OSA) is associated with sympathetic hyperactivity, excessive nocturnal sweating, sleepiness, and neurobehavioral cognitive alterations. However, it not well known if consequences of OSA are independent from autonomic Thus, we assessed the association between polysomnographic, autonomic, tests performance in patients. Methods Fifty eight patients (53 male) were administered questionnaires assessing demographic, Epworth, Beck Depression Inventory, Syndrom Kurz test (SKT), Trail Making part B (TMT-B), Frontal Assessment Battery (FAB) tests. Spectral analysis heart rate variability (HRV) night sweating symptoms (NSwS) score used to assess function. Results Global function (SKT) was normal mild-moderate (M-OSA) severe (S-OSA) In S-OSA AHI correlated TMT-B ( r  = 0.30 P  = −0.31  = −0.45  =   = 0.29  = −0.39  = −0.49 Conclusion dysfunction predominance drive occur Abnormal frontal hyperactivity related oxygen desaturation, but each other. We conclude that changes imbalance take place independently other, suggesting different pathophysiological pathways.