Genetic ablation of IRAK4 kinase activity inhibits vascular lesion formation
作者： Mark Rekhter , Kirk Staschke , Thomas Estridge , Pamela Rutherford , Nancy Jackson
DOI: 10.1016/J.BBRC.2007.12.186
关键词: Kinase activity 、 Lesion 、 Immunology 、 Kinase 、 Inflammation 、 Receptor antagonist 、 Signal transduction 、 Receptor 、 IRAK4 、 Cancer research 、 Biology
摘要: … IL-1 RA data are consistent with earlier demonstrations that pharmacological inhibition of IL-1 … that the size of carotid artery (defined as EEL area) was significantly smaller in IRAK4-ki/…
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