Identification and optimization of indolo[2,3-c]quinoline inhibitors of IRAK4.
作者： L. Nathan Tumey , Diane H. Boschelli , Niala Bhagirath , Jaechul Shim , Elizabeth A. Murphy
DOI: 10.1016/J.BMCL.2014.03.056
关键词:
摘要: … the SAR around the cyanophenyl ‘headpiece’ and the quinoline core. Generally, mixtures of 7 and 9-substituted indolo[2,3-c]quinolines were made by taking advantage of the oxidative …
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