作者: S P Miller , V A Marinkovich , D H Riege , W J Sell , D L Baker
DOI: 10.1093/CLINCHEM/30.9.1467
关键词: Allergy 、 Mast (sailing) 、 Immunology 、 Test chamber 、 Allergen 、 Allergen specific IgE 、 Immunoglobulin E 、 Allergy testing 、 Antibody 、 Computer science
摘要: The MAST Immunodiagnostic Test System was developed to provide a comprehensive, simple means for the in vitro measurement of multiple antigens or antibodies. first commercial application system incorporates several novel features cost-effective diagnosis IgE-mediated allergy clinical laboratory physician's office. basis is unique analytical test chamber, which contains cellulose thread as solid-phase matrix and allows results from single assay. This chamber both positive negative controls requires no volume-dependent pipetting steps. Immunographic exposure onto high-speed Polaroid instant film quantifying with an automatic recording infrared-transmittance densitometer. are easily interpreted by using patient record provided system. greatly simplifies testing allergen-specific IgE, while retaining specificity sensitivity. Currently, one can simultaneously measure picomoles IgE up 35 different allergen classes. In addition testing, technology applicable other immunodiagnostic profiles.