Perfusion in Renal Dysfunction

摘要: In normal conditions, the kidney receives 20%-25% of cardiac output (VB). Thus, it not surprising that several blood-borne endogenous or exogenous nephrotoxic substances (radiocontrast media, amynoglycosides, pigments, immunocomplexes etc.) can cause a disturbance renal function, which is principally be related to damage microvascular network and possibly leading acute failure (ARF). However, term “renal vascular injury” usually indicates pathophysiologic consequences shortage blood supply occurring in many clinical settings, including trauma hemorrhage, surgical interventions burns, ultimately occurrence prerenal ARF. Due pathophysiological factors, medulla particularly at risk ischemic (1), ARF associated extensive anatomofunctional deepest region kidney.