Proteomic fingerprinting of human ivf-derived embryos: identification of biomarkers of developmental potential
作者： Sergio C. Oehninger , Silvina Bocca , O. John Semmes , Lisa H. Cazares
DOI:
关键词: Embryo 、 Biomarker discovery 、 Bioinformatics 、 Identification (biology) 、 Biology 、 Biomarker (medicine) 、 Probable diagnosis
摘要: The present invention discloses biomarkers and biomarker combinations that have prognostic value as predictors of the developmental potential individual IVF-derived human embryos. In particular, this are useful to classify an embryo with implantation competence after uterine transfer or incompetence. addition, can be detected by non-invasive methods do not harm developing embryo. Also disclosed kits for prediction detect invention, well using a plurality classifiers make probable diagnosis potential.
google.de 参考文章(24)
Edmond Confino, Ralph R. Kazer, Xingqi Zhang, Compositions and methods for determining oocyte development potential ,(2005)
Yuan Q. Yao, David H. Barlow, Ian L. Sargent, Differential Expression of Alternatively Spliced Transcripts of HLA-G in Human Preimplantation Embryos and Inner Cell Masses Journal of Immunology. ,vol. 175, pp. 8379- 8385 ,(2005) , 10.4049/JIMMUNOL.175.12.8379
T. William Hutchens, Tai-Tung Yip, Surface-enhanced photolabile attachment and release for desorption and detection of analytes ,(1998)
Egisto Boschetti, William E. Rich, Tai-Tung Yip, Lee O. Lomas, Protein interaction difference mapping ,(2003)
T. William Hutchens, Tai-Tung Yip, Use of retentate chromatography to generate difference maps ,(1998)
Ben A. Hitt, Emmanuel F. Petricoin, Peter J. Levine, Lance A. Liotta, Process for discriminating between biological states based on hidden patterns from biological data ,(2001)
Shang-Mian Yie, Clifford L. Librach, Detection of hla-g ,(2000)
Srinivasa Nagalla, Mike Gravett, Ron Rosenfeld, Proteomic analysis of biological fluids ,(2004)
Catherine A. Vandevoort, Dennis R. Stewart, Relaxin levels correlated to ivf/et pregnancy success ,(1998)
Zhen Zhang, Hong Zhang, System and methods for processing biological expression data ,(2002)