Are Triptan Drugs Safe and Effective for Use in the Prevention of Menstrually Related Migraines (MRMs)

摘要: Objective: The objective of this selective EBM review is to determine whether or not Triptan drugs are safe and effective for use in the prevention menstrually related migraines (MRMs). Study Design: Review two English language randomized controlled trials one pilot control trial Data Sources: Randomized comparing a placebo group were found using Medline, PubMed, OVID Outcomes Measured: Incidence MRM based on patient self-report; number relapses; patients’ subjective evaluations effectiveness questionnaire; adverse effects treatment Results: Two study included review. Oral shown be benefit Conclusions: results reviewed demonstrate that oral drugs, given short-term, at preventing However, RCTs, some migraineurs experienced post-treatment attacks. There clear explanation these attacks; further studies need conducted allow more flexible dosing order ensure being treated during their perimenstrual period (PMP). Additionally, should schedules, dosages, duration treatment, routes administration as well efficacy within class MRMs.