Cytotoxicity of fly-ash in alveolar macrophages from hypothyroid rats.
作者： W.K. Liu , C.C. Wong
DOI: 10.1016/0887-2333(89)90051-9
关键词: Secretion 、 Lactate dehydrogenase 、 Macrophage 、 Cytotoxicity 、 Internal medicine 、 Cell culture 、 Pulmonary alveolus 、 Lysosome 、 Endocrinology 、 Acid phosphatase 、 Pathology 、 Biology
摘要: Abstract Fly-ash particles of a diameter smaller than 2 μ were collected from the electrostatic precipitator coal-fired power plant, and their cytotoxicity was studied in culture using alveolar macrophages healthy hypothyroid rats. The mortality rate secretion rates cytoplasmic (lactate dehydrogenase) lysosomal (acid phosphatase β-glucuronidase) enzymes into medium greater rats control macrophages. Electron microscopy showed retraction filapodia, loss ruffled membrane distortion cell shape These results demonstrate that fly-ash enhanced rats, indicate normal functions are impaired by changes thyroid status.
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