作者: Rachel P. Espiritu , Ann E. Kearns , Kristin S. Vickers , Clive Grant , Euijung Ryu
DOI: 10.1210/JC.2011-1486
关键词: Endocrinology 、 Primary hyperparathyroidism 、 Context (language use) 、 Internal medicine 、 Surgery 、 Hyperparathyroidism 、 Parathyroidectomy 、 Medicine 、 Thyroid disease 、 Case-control study 、 Thyroid 、 Depression (differential diagnoses)
摘要: Context: Patients with primary hyperparathyroidism (PHP) often report nonspecific symptoms including mood disturbances. Objective: The objective of the study was to determine frequency depression in PHP and assess its response parathyroidectomy. Methods: A case-control at a referral center Rochester, MN, performed Patient Health Questionnaire-9 (PHQ-9) assessments observed (n = 81) surgical 88) benign nontoxic thyroid disease 85) baseline 1, 3, 6, 12 months after surgery or initial questionnaire PHP. Baseline PHQ-9 scores their were evaluated. Results: groups similar gender history, but patients older. 1.71 points higher than controls adjusting for age (P .004). Clinically significant (≥10) twice as common (31.4%) compared subjects (15.3%). Parathyroidectomy resulted signific...