Oncogene-specific activation of tyrosine kinase networks during prostate cancer progression
作者： J. M. Drake , N. A. Graham , T. Stoyanova , A. Sedghi , A. S. Goldstein
关键词: Cyclin-dependent kinase 9 、 Protein tyrosine phosphatase 、 ROR1 、 Platelet-derived growth factor receptor 、 Receptor tyrosine kinase 、 Bruton's tyrosine kinase 、 Proto-oncogene tyrosine-protein kinase Src 、 Biology 、 Cancer research 、 Tyrosine phosphorylation
摘要: Dominant mutations or DNA amplification of tyrosine kinases are rare among the oncogenic alterations implicated in prostate cancer. We demonstrate that castration-resistant prostate …
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