作者: David M. Sabatini , Dos D. Sarbassov , Do-hyung Kim
DOI:
关键词: Biology 、 Nucleic acid 、 Biochemistry
摘要: The invention describes isolated mTOR-associated proteins (“mTOR-APs”) as well variants and fragments thereof the nucleic acids encoding them. also vectors host cells containing acid an mTOR-AP polypeptide methods for producing polypeptide. Also described are screening compounds which modulate activity treating or preventing a disorder that is responsive to modulation.