Synthesis and properties of pH and temperature sensitive P(NIPAAm-co-DMAEMA) hydrogels.
作者： Bo Wang , Xiao-Ding Xu , Zong-Chun Wang , Si-Xue Cheng , Xian-Zheng Zhang
DOI: 10.1016/J.COLSURFB.2008.01.001
关键词: Moiety 、 Temperature sensitive 、 Polymer chemistry 、 Acrylic resin 、 Chemistry 、 Monomer 、 Radical polymerization 、 Swelling 、 Kinetics 、 Self-healing hydrogels
摘要: In order to investigate the influence of continuous alkylamide sequence having pH sensitive unit on temperature sensitivity poly(N-isopropylacrylamide) (PNIPAAm)-based hydrogel, a monomer, N-(2-(dimethylamino) ethyl)-methacrylamide (DMAEMA), an ethylamide group as well aliphatic tertiary amino group, was designed and synthesized. Hydrogels based NIPAAm DMAEMA were prepared via free radical polymerization. The resulted P(NIPAAm-co-DMAEMA) hydrogels characterized in terms maximum swelling ratio, kinetics, response effect pH. data obtained show that novel have strong desire respond external stimuli. Importantly, because containing isopropylamide pendant groups from PNIPAAm PDMAEMA, incorporation moiety not only provides sensitivity, but also maintains thermal properties hydrogels, even molar percentage reaches 14 mol%.
elsevier.com
sci-hub.se 参考文章(45)
Takashi Miyata, Noriko Asami, Tadashi Uragami, A reversibly antigen-responsive hydrogel Nature. ,vol. 399, pp. 766- 769 ,(1999) , 10.1038/21619
Atsushi Suzuki, Toyoichi Tanaka, Phase transition in polymer gels induced by visible light Nature. ,vol. 346, pp. 345- 347 ,(1990) , 10.1038/346345A0
Xiao-Ding Xu, Xian-Zheng Zhang, Si-Xue Cheng, Ren-Xi Zhuo, John F. Kennedy, A strategy to introduce the pH sensitivity to temperature sensitive PNIPAAm hydrogels without weakening the thermosensitivity Carbohydrate Polymers. ,vol. 68, pp. 416- 423 ,(2007) , 10.1016/J.CARBPOL.2006.11.019
E Díez‐Peña, I Quijada‐Garrido, P Frutos, JM Barrales‐Rienda, None, Analysis of the swelling dynamics of crosslinked P(N-iPAAm-co-MAA) copolymers, the corresponding homopolymers and their interpenetrating networks. Kinetics of water penetration into the gel above the pKaof MAA comonomeric units Polymer International. ,vol. 52, pp. 956- 965 ,(2003) , 10.1002/PI.1139
Takao Aoyagi, Mitsuhiro Ebara, Kiyotaka Sakai, Yasuhisa Sakurai, Teruo Okano, Novel bifunctional polymer with reactivity and temperature sensitivity. Journal of Biomaterials Science-polymer Edition. ,vol. 11, pp. 101- 110 ,(2000) , 10.1163/156856200743526
Xiao-Ding Xu, Xian-Zheng Zhang, Bo Wang, Si-Xue Cheng, Ren-Xi Zhuo, Zong-Chun Wang, Fabrication of a novel temperature sensitive poly(N-isopropyl-3-butenamide) hydrogel Colloids and Surfaces B: Biointerfaces. ,vol. 59, pp. 158- 163 ,(2007) , 10.1016/J.COLSURFB.2007.05.005
Xiao-Ding Xu, Xian-Zheng Zhang, Jie Yang, Si-Xue Cheng, Ren-Xi Zhuo, Ya-Qun Huang, Strategy to introduce a pendent micellar structure into poly(N-isopropylacrylamide) hydrogels. Langmuir. ,vol. 23, pp. 4231- 4236 ,(2007) , 10.1021/LA063485Z
Françoise M Winnik, Phase transition of aqueous poly-(N-isopropylacrylamide) solutions: a study by non-radiative energy transfer Polymer. ,vol. 31, pp. 2125- 2134 ,(1990) , 10.1016/0032-3861(90)90085-D
Masahiko Annaka, Chiduru Tanaka, Takayuki Nakahira, Masaaki Sugiyama, Takao Aoyagi, Teruo Okano, Fluorescence study on the swelling behavior of comb-type grafted poly(N-isopropylacrylamide) hydrogels Macromolecules. ,vol. 35, pp. 8173- 8179 ,(2002) , 10.1021/MA020683Y
Yong Li, Toyoichi Tanaka, Kinetics of swelling and shrinking of gels Journal of Chemical Physics. ,vol. 92, pp. 1365- 1371 ,(1990) , 10.1063/1.458148