Somatic mutations in histiocytic sarcoma identified by next generation sequencing.
作者： Qingqing Liu , Keith Tomaszewicz , Lloyd Hutchinson , Jason L. Hornick , Bruce Woda
DOI: 10.1007/S00428-016-1965-2
关键词: Histiocytic sarcoma 、 Somatic cell 、 Kinase activity 、 Carcinogenesis 、 Neoplasm 、 Germline mutation 、 Histiocyte 、 Germline 、 Pathology 、 Cancer research 、 Biology
摘要: … potential benefits of BRAF-targeted therapy. BRAF mutation G466R (VF of 29.6 %) identified in our study is located at P loop, which potentially modulates BRAF kinase activity. A similar …
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Neerav Shukla, Rachel Kobos, Thomas Renaud, Julie Teruya-Feldstein, Anita Price, Linda McAllister-Lucas, Peter Steinherz, Successful treatment of refractory metastatic histiocytic sarcoma with alemtuzumab Cancer. ,vol. 118, pp. 3719- 3724 ,(2012) , 10.1002/CNCR.26712
Jessica L. Heath, Shelly E. Burgett, Ana M. Gaca, Ronald Jaffe, Daniel S. Wechsler, Successful treatment of pediatric histiocytic sarcoma using abbreviated high‐risk leukemia chemotherapy Pediatric Blood & Cancer. ,vol. 61, pp. 1874- 1876 ,(2014) , 10.1002/PBC.25100
Steven A. Stacker, Marc G. Achen, The VEGF signaling pathway in cancer: the road ahead. Chinese Journal of Cancer. ,vol. 32, pp. 297- 302 ,(2013) , 10.5732/CJC.012.10319
Elias Campo, N Lee Harris, Elaine S Jaffe, Stefano A Pileri, Harald Stein, Jurgen Thiele, James W Vardiman, None, WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues ,(2017)
Gavin M. Wright, Hongdo Do, Jonathan Weiss, Naveed Z. Alam, Vivek Rathi, Marzena Walkiewicz, Thomas John, Prudence A. Russell, Alexander Dobrovic, Mapping of actionable mutations to histological subtype domains in lung adenocarcinoma: implications for precision medicine Oncotarget. ,vol. 5, pp. 2107- 2115 ,(2014) , 10.18632/ONCOTARGET.1840
A. Douglas Laird, James G. Christensen, Guangmin Li, Jeremy Carver, Kimberly Smith, Xiaohua Xin, Katherine G. Moss, Sharianne G. Louie, Dirk B. Mendel, Julie M. Cherrington, SU6668 inhibits Flk-1/KDR and PDGFRβ in vivo, resulting in rapid apoptosis of tumor vasculature and tumor regression in mice The FASEB Journal. ,vol. 16, pp. 681- 690 ,(2002) , 10.1096/FJ.01-0700COM
Barbara M. Osborne, Bruce Mackay, True Histiocytic Lymphoma with Multiple Skin Nodules Ultrastructural Pathology. ,vol. 18, pp. 241- 246 ,(1994) , 10.3109/01913129409016296
Heounjeong Go, Yoon Kyung Jeon, Jooryung Huh, Suk Jin Choi, Yoo-Duk Choi, Hee Jeong Cha, Hyun-Jung Kim, Gyeongsin Park, Sookee Min, Ji Eun Kim, Frequent detection of BRAFV600E mutations in histiocytic and dendritic cell neoplasms Histopathology. ,vol. 65, pp. 261- 272 ,(2014) , 10.1111/HIS.12416
Antoni Ribas, Keith T. Flaherty, BRAF targeted therapy changes the treatment paradigm in melanoma Nature Reviews Clinical Oncology. ,vol. 8, pp. 426- 433 ,(2011) , 10.1038/NRCLINONC.2011.69
R E Board, G Ellison, M C M Orr, K R Kemsley, G McWalter, L Y Blockley, S P Dearden, C Morris, M Ranson, M V Cantarini, C Dive, A Hughes, Detection of BRAF mutations in the tumour and serum of patients enrolled in the AZD6244 (ARRY-142886) advanced melanoma phase II study. British Journal of Cancer. ,vol. 101, pp. 1724- 1730 ,(2009) , 10.1038/SJ.BJC.6605371