Mitochondrial Metabolism and Insulin Action

摘要: The major disease epidemics of modern society are not those contagion, but the result lifestyle imposed upon our genetic pre-disposition. Unrestricted access to calorie-dense food, along with a reduction in physical activity, has resulted rapid rise metabolic disorders. One such condition, type 2 diabetes (T2D), increased dramatically recent times, International Diabetes Foundation estimating that 371 million people world‐ wide have T2D, this number expected increase greater than 550 by 2030 (http://www.idf.org/diabetesatlas/5e/Update2012). T2D is characterized fasting blood glucose levels higher 7.0 mM or two-hour 11.1 after tolerance test. rarely occurs isolation and frequently associated comorbidities, including obesity, dyslipidemia, cardiovascular disease, inflammation, collectively referred as syndrome.