Vertebral osteomyelitis caused by non-tuberculous mycobacteria: Predisposing conditions and clinical characteristics of six cases and a review of 63 cases in the literature

摘要: Background Several case series have reported on clinical and radiographic characteristics of patients with vertebral osteomyelitis (VO) caused by non-tuberculous mycobacteria (NTM). However, only a few were included, systematic reviews are still lacking. The aim this study was to update summarise the pre-disposing conditions, such cases due NTM. Methods In study, review conducted English-language literature from 1961-2014 investigate conditions VO Also, six additional diagnosed in hospitals described; these included an analysis total 69 NTM VO. Results most common species, regardless presence HIV co-infection, M. avium Complex followed xenopi. Ten infection had median CD4 lymphocyte count 320/mm(3) (range = 41-465/mm(3)) at time diagnosis infections occurred earlier age more often involved thoracic spine than without infection. Pre-disposing trauma or surgery 14.5% (10/69) cases. A variety immunosuppressive diseases observed 49.3% patients, including 10 corticosteroids used 27.5% Surgery performed 67.6% improvement 80.6%. Conclusion should be considered immunocompromised indolent confirmation tuberculosis.