(S)-N-(N-(((2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)sulfamoyl)-5-oxopyrrolidine-2-carboxamide
作者： Ravil Khaybullin , Xiao Liang , Xin Qi
DOI: 10.3390/M864
关键词: Chemistry 、 Carboxamide 、 Sulfamide 、 Stereochemistry 、 Adenosine 、 Aminoacyl-tRNA synthetase activity 、 Derivative (chemistry)
摘要: Aminoacyl sulfamides represent a family of high-affinity inhibitors the specific aminoacyl tRNA synthetase activity. In this paper we describe synthesis novel sulfamide adenosine derivative 4 bearing pyroglutamyl fragment (pGlu-SA).
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