Corticosteroid therapy for the treatment of acute attacks of crystal-induced arthritis: an effective alternative to nonsteroidal antiinflammatory drugs.

摘要: To evaluate glucocorticoids as an alternative to nonsteroidal antiinflammatory drugs in patients with crystal-induced arthritis, a study was conducted 27 acute attacks of gout or chondrocalcinosis. Patients contraindications drug therapy were given either single intramuscular injection 7 mg betamethasone (group B, n = 10) or, if they receiving anticoagulant therapy, intravenous 125 methylprednisolone C, 7). The remaining A, diclofenac dosage 150 per day for three days then 75 days. Efficacy evaluated based on the self-evaluated subjective improvement (%) and severity joint swelling 1, 3, 6. Both parameters improved promptly all groups. C-reactive protein decreased between baseline Few had relapses. Glucocorticoid well tolerated. Our data show that glucocorticoid is safe effective arthritis risk factors intolerance drugs.