Serologic Tests for the Detection of Human Immunodeficiency Virus Infection

作者: J. Richard George , Gerald Schochetman

DOI: 10.1007/978-1-4684-0514-9_5

关键词: NeopterinSeroprevalenceImmunologic TestsViremiaHuman immunodeficiency virus (HIV)SerologyAntibodyVirologyAntigenMedicine

摘要: Persons infected with the human immunodeficiency virus (HIV) have a spectrum of clinical features, ranging from persons who are but appear completely healthy to those rapid disease progression and mortality. All groups, regardless stage, possess several biologic indicators viral infection or replication (Figure 5.1). These include viremia, antibodies against proteins, circulating nonspecific markers such as neopterin, beta2-microglobulins, T4 cell counts. A variety immunologic tests currently exists for detection protein antigens. assays permitted testing programs protect blood supply units conduct seroprevalence surveys define epidemic. More recently, presence absence been used predict onset disease.

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