Agammaglobulinemia, malabsorption and rheumatoid-like arthritis

摘要: Abstract A patient with agammaglobulinemia, malabsorption and a rheumatoid-like arthritis is described. The malabsorptive process considered to be etiologically distinct from adult celiac disease because of the patient's failure respond gluten-free diet. In addition, although jejunal biopsy specimen showed absence villi, infiltration inflammatory cells in lamina propria was unusually dense composed almost entirely lymphocytes. An attempt relate small intestinal bacterial overgrowth or gamma globulin deficiency per se unsuccessful. serum decay fecal loss injected were measured. There no evidence increased catabolism excessive globulin. similarities this arthritic rheumatoid are emphasized. Superimposed on severe degree osteomalacia caused part by endogenous calcium. interrelationships various facets explained. course could not related replacement therapy other aspects process.