作者: L. Black
关键词: Antigen 、 Titer 、 Half-life 、 Intradermal injection 、 Immunology 、 Allergy 、 Antibody 、 Foot-and-mouth disease 、 Vaccination 、 Medicine
摘要: BHK cell derivatives, saponin and aluminium hydroxide, all of which are commonly present in foot-and-mouth disease vaccines, were injected subcutaneously into 10 cattle the serum levels anti-BHK reagins passive haemagglutinating antibodies followed. The reaginic rose to a peak titre one two weeks after stimuli waned during third week. They had half life about three days, assuming exponential decay, generally undetectable four last contact with antigen. Passive haemagglutinins slower develop or more usually required produce detectable antibody levels. also subside demonstrable for at least antigen most cases. Clinical reactions provoked by intradermal injection lysate sensitised not correlated reagin haemagglutinin their ratio another time reactions. reasons this discussed.