Galactoligosaccharide and a prebiotic blend improve colonic health and immunity of adult dogs.

作者: Mariana Fragoso Rentas , Raquel Silveira Pedreira , Mariana Pamplona Perini , Larissa Wünsche Risolia , Rafael Vessecchi Amorim Zafalon

DOI: 10.1371/JOURNAL.PONE.0238006

关键词: Analysis of varianceLactic acidRespiratory burstGalactooligosaccharideStatistical significanceChemistryFood scienceFecesImmunityPrebiotic

摘要: This study aimed to evaluate the effects of two prebiotics in different concentrations on nutrient digestibility, fermentative products and immunological variables adult dogs. Twenty-four dogs were randomly divided into six blocks according their metabolic body weights (BW0.75); within these groups, randomized four treatments: control without (CO); inclusion 0.5% prebiotic blend Yes-Golf (B1); 1.0% galactooligosaccharide (GOS); (B2). The experiment lasted 30 days, with 20 days adaptation 10 stool blood collection. Results analyzed for normality means separated by ANOVA adjusted Tukey test at significance level 5.0%. Prebiotic supplementation had no effect apparent digestibility coefficients (ADC), total production fecal scores (p > 0.05). Prebiotics evaluated also did not alter pH, nor ammonia, lactic acid, short chain fatty acids (SCFA) most branched (BCFA) addition GOS decreased concentration iso-valeric acid = 0.0423). Regarding variables, IgA influenced treatments. Treatments B2 increased number polymorphonuclear cells, as well oxidative burst relation treatments B1 CO < 0.0001). Treatment improved rate S. aureus phagocytosis 0.0111), both a better index E. coli than treatment 0.0067). In conclusion, there was indication that immunity healthy

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