Glucan-Based Macrophage Stimulators

作者: David L. Williams , Antje Mueller , William Browder

DOI: 10.1007/BF03259335

关键词: PharmacotherapySepsisSurgical patientsSepsis syndromeSurgical Intensive CareIntensive care medicineMedicineMacrophageCritically ill

摘要: Sepsis and sepsis syndrome are significant causes of morbidity mortality in critically ill surgical patients. Despite technological therapeutic advances critical care, continues to be a pivotal factor 20 50% deaths intensive care units. It is clear that alternative approaches the prevention and/or treatment must found.

参考文章(52)
Zanetti G, Baumgartner Jd, Glauser Mp, Anti-endotoxin antibodies and other inhibitors of endotoxin. New horizons (Baltimore, Md.). ,vol. 1, pp. 110- ,(1993)
Holt Tm, Cook Ja, Dougherty Wj, Enhanced sensitivity to endotoxin induced by the RE stimulant, glucan. Circulatory shock. ,vol. 7, pp. 225- ,(1980)
Solomkin Js, Antrum Rm, Monocyte dysfunction in severe trauma: evidence for the role of C5a in deactivation. Surgery. ,vol. 100, pp. 29- 37 ,(1986)
S. M. Opal, G. J. Slotman, T. J. Iberti, J. C. Sadoff, M. P. Shelly, R. L. Greenman, W. A. Knaus, R A Balk, C. J. Fisher, J. F. Labrecque, J.-D. Dhainaut, J. P. Pribble, B. W. Thompson, M. J. Shapiro, H. D. Reines, E. C. Rackow, M. A. Catalano, Recombinant human interleukin 1 receptor antagonist in the treatment of patients with sepsis syndrome JAMA. ,vol. 271, pp. 1836- 1843 ,(1994)
Richard V. McCloskey, Richard C. Straube, Corazon Sanders, Craig R. Smith, Susan M. Smith, Treatment of Septic Shock with Human Monoclonal Antibody HA-1A Annals of Internal Medicine. ,(1994)
J de Felippe Junior, M da Rocha e Silva Júnior, FM Maciel, NF Mendes, None, Infection prevention in patients with severe multiple trauma with the immunomodulator beta 1-3 polyglucose (glucan). Surgery gynecology & obstetrics. ,vol. 177, pp. 383- 388 ,(1993)
J. Leibovici, Y. Stark, T. Eldar, G. Brudner, M. Wolman, Mechanism of the Inhibitory Effect of Levan on Experimental Tumors Recent results in cancer research. ,vol. 75, pp. 173- 179 ,(1980) , 10.1007/978-3-642-81491-4_27