Compliance and satisfaction with switching from an immediate-release to sustained-release formulation of valproate in people with epilepsy

摘要: Abstract Objective. The goal of our work was to assess compliance and patient satisfaction with switching from sodium valproate Depakine Chrono in patients epilepsy. Methods. Clinical, demographic, behavioral details assessing were collected using self-completion questionnaires at the time inclusion study 3 months after day. Results. Data 2031 respondents eight European countries. There significant differences between 1 2 seizure frequency, reported side effects, compliance, satisfaction. Conclusion. Findings suggest that results an increase seizure-free rates, a reduction improvement level modest