Macrocycle-functionalized polystyrene beads as specific absorbers
作者： Pernilla Sund , Carl-Eric Wilén
DOI: 10.1016/J.REACTFUNCTPOLYM.2015.02.004
关键词: Polystyrene 、 Monomer 、 Chemistry 、 Phenacyl 、 Polymer 、 Polymer chemistry 、 Annulation 、 Triazole 、 Bromophenol blue 、 Bromocresol green
摘要: Abstract Crosslinked polystyrene beads were first functionalized with phenacyl ester linkers, and a series of four macrocycles different ring sizes synthesized from these linkers. The built amide-linked monomers coupled by conventional peptide-synthesis methods. Annulation was achieved copper(I)-catalyzed intramolecular azide–alkyne cycloaddition to give triazole linked macrocycles. cleaved the polymer hydrazinolysis or saponification. structures confirmed high-resolution nuclear magnetic resonance (NMR) liquid chromatography–mass spectrometry (LC–MS) analysis. ability polymers selectively bind compounds mixture aromatic derivatives in ethanol tested. prepared supported found bromophenol blue bromocresol green non-covalently an association constant 160–490 M −1 .
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