作者: Russell D. Hull , Jack Hirsh , Cedric J. Carter , Gary E. Raskob , Gerald J. GilI
关键词: Ventilation/perfusion ratio 、 Pulmonary function testing 、 Prospective cohort study 、 Venous thrombosis 、 Perfusion 、 Medicine 、 Lung 、 Radiology 、 Pulmonary angiography 、 Pulmonary embolism
摘要: Differing opinions about the value of ventilation-perfusion lung scanning have created controversy concerning correct approach to diagnosis pulmonary embolism. In a prospective study 305 consecutive patients with clinically suspected embolism and abnormal perfusion scans, we evaluated role scanning, angiography, objective testing for venous thrombosis in diagnostic process. Segmental or greater defects ventilation mismatch high probability (86 percent) Contrary current clinical practice, however, ruling against by "low probability" scan pattern is incorrect, even an improved technique imaging; frequency these ranged from 25 40 percent. Objective provides practical alternative performing angiography work-up; providing endpoint commencing anticoagulant therapy, positive result obviates need further 20 30 percent patients.