Avaliação da resposta inflamatória em cães naturalmente infectados por Leishmania infantum Inflammatory response evaluation in naturally infected dogs by Leishmania infantum

作者: Diana Célia Sousa Nunes-Pinheiro , Belarmino Eugênio Lopes-Neto , Glauco Jonas Lemos Santos , Adam Leal Lima , José Claudio

DOI:

关键词: FibrinogenImmunologyBiologyAcquired immune systemTBARSInflammatory responseVisceral leishmaniasisThiobarbituric acidLeishmania infantumAsymptomatic

摘要: Canine visceral leishmaniasis (CVL) is manifested by tissue damage in dogs infected with Leishmania infantum and presented as asymptomatic or symptomatic disease. Different clinical pictures are associated the host response, which triggered inflammatory response specific immune response. This study aimed to evaluate L. naturally dogs. Dogs (n=12) were divided into two groups: seropositive (n=6) seronegative (n=6). Blood samples collected for determination of total leukocyte neutrophil counts serum levels C-reactive protein (CRP), fibrinogen (FIB) thiobarbituric acid reactive species (TBARS). Data expressed mean standard deviation compare groups Student t test was used (p < 0.05). Seropositive animals showed elevated neutrophils count 0.05), CRP above reference values 0.05) greater TBARS compared

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