Tracking the Hemodynamic Responses to Reward and Punishment in the Striatum
作者： M. R. Delgado , L. E. Nystrom , C. Fissell , D. C. Noll , J. A. Fiez
DOI: 10.1152/JN.2000.84.6.3072
关键词: Psychology 、 Cerebral cortex 、 Ventral striatum 、 Neuroscience 、 Reward system 、 Striatum 、 Brain stimulation reward 、 Functional magnetic resonance imaging 、 Basal ganglia 、 Punishment (psychology)
摘要: Research suggests that the basal ganglia complex is a major component of neural circuitry mediates reward-related processing. However, human studies have not yet characterized response to an isolated reward, as has been done in animals. We developed event-related functional magnetic resonance imaging paradigm identify brain areas are activated after presentation reward. Subjects guessed whether value card was higher or lower than number 5, with monetary rewards incentive for correct guesses. They received punishment, neutral feedback on different trials. Regions dorsal and ventral striatum were by paradigm, showing differential responses reward punishment. Activation sustained following feedback, but decreased below baseline punishment feedback.
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