Tyrosine kinase gene fusions in cancer: translating mechanisms into targeted therapies
作者： Sandrine Medves , Jean-Baptiste Demoulin
DOI: 10.1111/J.1582-4934.2011.01415.X
关键词: MAP2K7 、 ROR1 、 Proto-oncogene tyrosine-protein kinase Src 、 ABL 、 Tyrosine kinase 、 Platelet-derived growth factor receptor 、 ASK1 、 Biology 、 Receptor tyrosine kinase 、 Cancer research
摘要: … Imatinib induces remission in leukaemia patients that are positive for BCR-ABL or PDGFR … A similar mechanism has been described in PDGFRA, PDGFRB and RET. Cancer point …
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