Senescent cell clearance by the immune system: Emerging therapeutic opportunities.

作者: Larissa G.P. Langhi Prata , Inna G. Ovsyannikova , Tamara Tchkonia , James L. Kirkland

DOI: 10.1016/J.SMIM.2019.04.003

关键词: Senescent cellPhenotypeImmunologyMedicineSecretionImmune systemChemokineMultiple Chronic DiseasesImmune DysfunctionDNA damage

摘要: … Senescent cells (SCs) arise from normal cells in multiple organs due to inflammatory, … cells that can secrete a range of pro-inflammatory and proteolytic factors as part of the senescence-…

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