PERIPHERAL GAS EXCHANGE

摘要: Gas exchange in any tissue or organ requires O2 delivery (and CO2 removal) along a transport pathway involving, sequentially, the lungs, heart, blood, circulation, and tissues. Convective factors governed mostly by circulation determine how much reaches each tissue, while diffusion underlies unloading to mitochondria. consumption may be limited these processes, alternatively set metabolic demand. The maximal amount of available mitochondria is not determined uniquely one step pathway, but all an integrated manner. Because steps are arranged series, poor function single significantly reduces transport, greater than normal such increases overall only slightly. When considering central peripheral limitations it evident that convective tissues depends part on (regional vascular conductances), diffusive periphery (especially blood flow). In both health disease, contribute at least area muscle during exercise, where system often stretched its limits.