Model for capillary-alveolar equilibration with special reference to O2 uptake in hypoxia.

作者: J. Piiper , P. Scheid

DOI: 10.1016/0034-5687(81)90121-3

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摘要: Abstract This paper presents a simple model for the study of diffusion limitation effects in capillary-alveolar gas transfer. The decisive parameter to determine extent is shown be dimensionless ratio D/(Qβ) (D, diffusing capacity, Q, blood flow; β, capacitance coefficient or effective solubility blood). predicts considerable pulmonary O 2 uptake hypoxia, which sets an upper limit level exercise at high altitude.

参考文章(20)
J. Piiper, MODEL ANALYSIS OF GAS EXCHANGE ORGANS IN VERTEBRATES Animals and Environmental Fitness: Physiological and Biochemical Aspects of Adaptation and Ecology#R##N#Invited Lectures. pp. 119- 132 ,(1980) , 10.1016/B978-0-08-024938-4.50012-4
John B. West, Peter D. Wagner, Predicted gas exchange on the summit of Mt. Everest Respiration Physiology. ,vol. 42, pp. 1- 16 ,(1980) , 10.1016/0034-5687(80)90100-0
J. Piiper, P. Dejours, P. Haab, H. Rahn, Oncepts and basic quantities in gas exchange physiology Respiration Physiology. ,vol. 13, pp. 292- 304 ,(1971) , 10.1016/0034-5687(71)90034-X
H. Bartels, W. Moll, PASSAGE OF INERT SUBSTANCES AND OXYGEN IN THE HUMAN PLACENTA. Pflügers Archiv: European Journal of Physiology. ,vol. 280, pp. 165- 177 ,(1964) , 10.1007/BF00363755
M. Meyer, U. Tebbe, J. Piiper, Solubility of inert gases in dog blood and skeletal muscle Pflügers Archiv: European Journal of Physiology. ,vol. 384, pp. 131- 134 ,(1980) , 10.1007/BF00584428
Johannes Piiper, Peter Scheid, Gas transport efficacy of gills, lungs and skin: Theory and experimental data Respiration Physiology. ,vol. 23, pp. 209- 221 ,(1975) , 10.1016/0034-5687(75)90061-4
Takeo Kawashiro, Alejandro Campos Carles, Steven F. Perry, Johannes Piiper, Diffusivity of various inert gases in rat skeletal muscle Pflügers Archiv: European Journal of Physiology. ,vol. 359, pp. 219- 230 ,(1975) , 10.1007/BF00587381
J. Piiper, M. Meyer, C. Marconi, P. Scheid, Alveolar-capillary equilibration kinetics of 13CO2 in human lungs studied by rebreathing Respiration Physiology. ,vol. 42, pp. 29- 41 ,(1980) , 10.1016/0034-5687(80)90102-4
P D Wagner, J B West, Effects of diffusion impairment on O 2 and CO 2 time courses in pulmonary capillaries. Journal of Applied Physiology. ,vol. 33, pp. 62- 71 ,(1972) , 10.1152/JAPPL.1972.33.1.62