Reflections on human tumor immunology.

摘要: The ultimate aim of tumor immunity studies in patients is to find therapeutical measures (for a recent review cancer immunotherapy see ref. 24). demonstration lymphocytes blood or the environment which react with tumorin vitro could indicate that immune recognition exist but effector mechanisms are inactive. past and present attempts T cell readministration after theirin activation did not meet expectations, however. In addition, procedure laborious demanding both for patient physician. Attention be directed therefore activate resident effectors, break anergy tolerance. This approach was exercised from beginning immunotherapeutical attempts. However, response by non-specific applied until now were efficient. It possible increased knowledge cytokine actions their production at large scale will provide new possibilities efficient manifestation potentiation an existing immunity.