Reevaluation of Digitalis Efficacy: New Light on an Old Leaf

摘要: Use of digitalis for the treatment patients with congestive heart failure and sinus rhythm remains controversial. To ascertain proper therapeutic role digitalis, we have critically appraised published clinical evidence efficacy using standardized methodologic criteria. A search English literature from 1960 to 1982 identified 736 articles, which 16 specifically addressed evaluation therapy rhythm. Only two double-blind, placebo-controlled trials provided clinically useful information. One study showed that digoxin could be withdrawn successfully in elderly stable failure. The other chronic an S3 gallop benefited therapy.