Fasting serum fatty acid-binding protein 4 level positively correlates with metabolic syndrome in hemodialysis patients.

作者: Jen-Pi Tsai , Hung-Hsiang Liou , Hsiang-Man Liu , Chung-Jen Lee , Ru-Ping Lee

DOI: 10.1016/J.ARCMED.2010.09.007

关键词: EndocrinologyHemodialysisMedicineAdiponectinMetabolic syndromeInsulin resistanceBody mass indexInternal medicineInsulinFatty acid-binding proteinWaist

摘要: Background and Aims Serum fatty acid-binding protein 4 (FABP4) level increases in patients with metabolic syndrome (MetS). The interrelationships between fasting FABP4 levels MetS have not been analyzed hemodialysis (HD) patients. Methods Fasting blood samples were obtained from 101 chronic HD was defined according to the diagnostic criteria of International Diabetes Federation. Results In total, 48 (47.5%) had MetS. positively correlated ( p = 0.022). Univariate linear regression analysis showed that pre-HD body weight 0.003), mass index total cholesterol (TCH) 0.042), insulin 0.014), homeostasis model assessment resistance (HOMA-IR; 0.015) serum levels, whereas high-density lipoprotein-cholesterol (HDL-C) 0.049) adiponectin 0.004) negatively Conclusions our TG, TCH, waist circumference independent predictors

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