Interaction of Malaria-Infected Cells with the Vascular Wall

摘要: Recent estimations confirm malaria as the most common infectious disease affecting human species. Worldwide, more than 2 billion people are at risk of infection. About 200 million cases occur every year and approximately them result in death patient, especially children endemic areas (Greenwood et al., 1987). Plasmodium falciparum infection is by far severe form malaria, which accounts for vast majority fatal cases. It owes its severity to frequency complications (White, 1986) The dangerous complication cerebral (CM), responsible about 80% all cases, although it develops only 0.5–1% episodes P. CM invariably lethal if untreated, also kills up 40% treated patients. recovery from occasionally accompanied permanent, disabling neurological sequelae (Marsh Greenwood, 1986; Phillips Warrell, World Health Organization Malaria Action Program, Warred