Tracking of unfamiliar odors is facilitated by signal amplification through anoctamin 2 chloride channels in mouse olfactory receptor neurons.

作者: Franziska Neureither , Nadine Stowasser , Stephan Frings , Frank Möhrlen

DOI: 10.14814/PHY2.13373

关键词: NeuroscienceOlfactory receptorChloride channelStimulus (physiology)OdorOlfactory epitheliumOlfactory cuesBiologyOdor perceptionAnatomySignal amplification

摘要: … To increase tracking motivation, mice were food deprived 3 days prior to testing. The body … by limiting food to 2–3 g/day for each mouse. Food was given after the daily tracking test. At …

参考文章(60)
William T. Nickell, Nancy K. Kleene, Steven J. Kleene, Mechanisms of neuronal chloride accumulation in intact mouse olfactory epithelium. The Journal of Physiology. ,vol. 583, pp. 1005- 1020 ,(2007) , 10.1113/JPHYSIOL.2007.129601
Emmanuelle Courtiol, Donald A. Wilson, The olfactory thalamus: unanswered questions about the role of the mediodorsal thalamic nucleus in olfaction. Frontiers in Neural Circuits. ,vol. 9, pp. 49- 49 ,(2015) , 10.3389/FNCIR.2015.00049
Hiroshi Kaneko, Ilva Putzier, Stephan Frings, U Benjamin Kaupp, Thomas Gensch, Chloride accumulation in mammalian olfactory sensory neurons. The Journal of Neuroscience. ,vol. 24, pp. 7931- 7938 ,(2004) , 10.1523/JNEUROSCI.2115-04.2004
Tadashi Nakamura, Geoffrey H. Gold, A cyclic nucleotide-gated conductance in olfactory receptor cilia Nature. ,vol. 325, pp. 442- 444 ,(1987) , 10.1038/325442A0
Makoto Kashiwayanagi, Hajime Kawahara, Kentaro Kanaki, Fumiko Nagasawa, Kenzo Kurihara, Ca2+ and Cl(-)-dependence of the turtle olfactory response to odorants and forskolin. Comparative Biochemistry and Physiology Part A: Physiology. ,vol. 115, pp. 43- 52 ,(1996) , 10.1016/0300-9629(95)02139-6
Marian Tsanov, Ehsan Chah, Richard Reilly, Shane M. O'Mara, Respiratory cycle entrainment of septal neurons mediates the fast coupling of sniffing rate and hippocampal theta rhythm European Journal of Neuroscience. ,vol. 39, pp. 957- 974 ,(2014) , 10.1111/EJN.12449
Johannes Reisert, Paul J. Bauer, King-Wai Yau, Stephan Frings, The Ca-activated Cl channel and its control in rat olfactory receptor neurons. The Journal of General Physiology. ,vol. 122, pp. 349- 363 ,(2003) , 10.1085/JGP.200308888
V. M. Milenkovic, O. Strauss, W. M. Aartsen, J. Wijnholds, B. H. F. Weber, H. L. Schulz, H. Stohr, J. B. Heisig, P. M. Benz, S. Schoberl, TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals. The Journal of Neuroscience. ,vol. 29, pp. 6809- 6818 ,(2009) , 10.1523/JNEUROSCI.5546-08.2009
Izumi Fukunaga, Manuel Berning, Mihaly Kollo, Anja Schmaltz, Andreas T. Schaefer, Two Distinct Channels of Olfactory Bulb Output Neuron. ,vol. 75, pp. 320- 329 ,(2012) , 10.1016/J.NEURON.2012.05.017
Gwendolyn M Billig, Balázs Pál, Pawel Fidzinski, Thomas J Jentsch, Ca2+-activated Cl− currents are dispensable for olfaction. Nature Neuroscience. ,vol. 14, pp. 763- 769 ,(2011) , 10.1038/NN.2821