Ventricular septal defect with increased pulmonary vascular resistance: Late results of surgical closure

摘要: Abstract The fate of 57 children who underwent surgical closure ventricular septal defect in the presence increased pulmonary vascular resistance was analyzed. Eighteen (32 percent) died at or immediately after operation. Seven late deaths, due to Eisenmenger syndrome, occurred 1 7 years Follow-up studies, including cardiac catheterization, were performed 25 survivors, 11 (mean 5 years) In patients operated on age 2 years, degree preoperative elevation largely determined prognosis: condition with mild (pulmonary less than one third systemic level) returned normal operation, exception. Patients more severe most often showed progressive disease; a few remained unchanged and that only Operative mortality rate high elevated during second year life before but three survivors. When first life, it generally decreased spontaneously (independently operation); early increase these cases is believed represent delayed maturation bed rather disease. overall results surgery associated level are unfavorable call for interruption natural history significant obstructive changes have taken place; this can be achieved by artery banding infancy.